The Rotonda di San Lorenzo is the most ancient church in Mantua. It is now sunk below the level of the Piazza della Erbe. It probably stands on the site of a Roman temple that was dedicated to the goddess Venus.
It was built during the reign of the Canossa family in the late 11th century. Inspired by the Holy Sepulchre church in Jerusalem and dedicated to the martyr St. Lawrence, it has a central plan and has maintained ancient features like the matronaeum (loggia for female faithful) and frescoes of the Byzantine school from the 11th-12th century. Another fresco fragment in the apse, portraying the Martyrdom of St. Lawrence, dates to the 15th century. The construction, according to the Lombard tradition, is in bricks, but has two columns and other details in marble, coming from ancient edifices.
Deconsecrated, it was used for dwellings, shops and stores, and at the beginning of the 20th century it was covered by other edifices. Later, it was restored and the external additions removed.
References:The Basilica of Santa Maria in Trastevere is one of the oldest churches of Rome. The basic floor plan and wall structure of the church date back to the 340s, and much of the structure to 1140-43. The first sanctuary was built in 221 and 227 by Pope Callixtus I and later completed by Pope Julius I.
The inscription on the episcopal throne states that this is the first church in Rome dedicated to Mary, mother of Jesus, although some claim that privilege belongs to the Basilica di Santa Maria Maggiore. A Christian house-church was founded here about 220 by Pope Saint Callixtus I (217-222) on the site of the Taberna meritoria, a refuge for retired soldiers. The area was made available for Christian use by Emperor Alexander Severus when he settled a dispute between the Christians and tavern-keepers.
The church underwent two restorations in the fifth and eighth centuries and in 1140-43 it was re-erected on its old foundations under Pope Innocent II.