Panagia Apsinthiotissa or Absinthiotissa is a Greek Orthodox monastery probably established in the 11h or 12th century as a Byzantine imperial foundation and continued to enjoy a degree of prominence in the Lusignan and Venetian periods. Leontios, the abbot in about 1222, was one of the delegates sent to report the plight of the Orthodox Church under Latin jurisdiction to the Patriarch Germanos II in the Empire of Nicaea. Neophytus, Archbishop of Cyprus, was also in Nicaea at the time, having been banished by the Latin authorities for refusing to take an oath of obedience to the Roman Pontiff. Boustronios tells us that the Queen of Cyprus worshipped at the monastery in 1486, the implication being that Panagia Apsinthiotissa was under the Roman Church. He also reports that pilgrimages were made to Apinthi and Antiphonitis on the fifteenth of August by all the people of Kyrenia. After the Ottoman conquest, the monastery became the property of the Orthodox Patriarch of Jerusalem and subordinate to the nearby Monastery of Saint Chrysostom in Koutsoventis.
The main church of the monastery appears to have been built in the 12th century and has a cross-in-square plan of the Byzantine type surmounted by a high dome. The narthex, on the west side, has simple Gothic rib vaulting and probably dates to the 15th century. Writing in 1918, George Jeffery describes the establishment as a ruin.
References:The Basilica of Santa Maria in Trastevere is one of the oldest churches of Rome. The basic floor plan and wall structure of the church date back to the 340s, and much of the structure to 1140-43. The first sanctuary was built in 221 and 227 by Pope Callixtus I and later completed by Pope Julius I.
The inscription on the episcopal throne states that this is the first church in Rome dedicated to Mary, mother of Jesus, although some claim that privilege belongs to the Basilica di Santa Maria Maggiore. A Christian house-church was founded here about 220 by Pope Saint Callixtus I (217-222) on the site of the Taberna meritoria, a refuge for retired soldiers. The area was made available for Christian use by Emperor Alexander Severus when he settled a dispute between the Christians and tavern-keepers.
The church underwent two restorations in the fifth and eighth centuries and in 1140-43 it was re-erected on its old foundations under Pope Innocent II.