The original small church was built from 1341 to 1346 to replace the old fort on the site. From 1480 to 1483 the city added a tower and from 1493 to 1504, a new nave was added.
After the Protestant Reformation in 1529, the Nydeggkirche was transformed into a warehouse for barrels, timber and grain, but in 1566 again served as worship space. Beginning in 1566 it was cleaned out and minor renovations made to the windows and walls. However, in 1568 the bell tower roof caught fire and was destroyed. The new roof was finished and the damaged clock work repaired by the end of May 1571. The large wrought iron cross which tops the main spire was built by Caspar Brükessel during the same time. The current tower's appearance mostly dates back to the 1571 reconstruction.
The later changes to the tower were fairly minor. For example, in 1625 four small embrasures or firing slits were broken out of the tower to help defend the city gate and in 1631 eight copper waterspouts were added to the roof.
Until 1721 it was a branch church of the Münster of Bern. Today's congregation forms part of the Reformed Churches of the Canton Bern-Jura-Solothurn.
In 1863, the church was extended to the west and an entrance from the Nydeggbrücke (Nydegg Bridge) was added. Then, from 1951 to 1953 a total renovation happened.
In 1956, bronze reliefs by Perincioli were inspired by medieval role models in front of San Zeno in Verona and the Cathedral of Hildesheim.References:
The Basilica of Santa Maria in Trastevere is one of the oldest churches of Rome. The basic floor plan and wall structure of the church date back to the 340s, and much of the structure to 1140-43. The first sanctuary was built in 221 and 227 by Pope Callixtus I and later completed by Pope Julius I.
The inscription on the episcopal throne states that this is the first church in Rome dedicated to Mary, mother of Jesus, although some claim that privilege belongs to the Basilica di Santa Maria Maggiore. A Christian house-church was founded here about 220 by Pope Saint Callixtus I (217-222) on the site of the Taberna meritoria, a refuge for retired soldiers. The area was made available for Christian use by Emperor Alexander Severus when he settled a dispute between the Christians and tavern-keepers.
The church underwent two restorations in the fifth and eighth centuries and in 1140-43 it was re-erected on its old foundations under Pope Innocent II.