The Monastery of Santa María de las Cuevas, also known as the Monastery of the Cartuja hosts today The Andalusian Contemporary Art Center (The Centro Andaluz de Arte Contemporáneo).
Legend holds that the area, in Moorish times, was honeycombed with caves made by potters for ovens and to obtain clay, and that after the capture of the city by Christians in the thirteenth century, an image of the virgin was revealed inside one of the caves, where supposedly it had been hidden. It prompted the construction of a chapel of Santa María de las Cuevas to house the venerated icon. In the 15th century, the archbishop of Seville, aided by the noble family of Medina, helped found a Franciscan monastery at the site. Later constructions were patronized by don Perafán de Ribera (who built the Casa de Pilatos). In the 15th century, monks of the cloistered order of Saint Bruno were housed in the monastery.
Christopher Columbus' remains were first interred at Valladolid, then at the Monastery of the Cartuja by the will of his son Diego. In 1542 the remains were transferred to Colonial Santo Domingo.
During the Napoleonic invasion, the monastery was sacked and used as barracks. After returning in 1812, the monastery was finally vacated with the general closure of monasteries in 1835–36.
Following the confiscation Englishman Charles Pickman acquired the monastery in 1839. Commencing production in 1841, Pickman established innovative manufacturing methods such as importing raw materials, the use of molds, using specialised machinery, mechanical arms and presses, utilising British ceramist experience while employing pottery workers from nearby Triana. The initial success of the factory led to La Cartuja de Sevilla becoming one of the most popular brands in Europe and in Latin American countries. Production continued until 1984. The bottle shaped kilns and tall chimney are the legacy of the ceramics factory.
From its origin as a small stronghold built by the ancient Illyrian tribe Dalmatae, becoming a royal castle that was the seat of many Croatian kings, to its final development as a large fortress during the Ottoman wars in Europe, Klis Fortress has guarded the frontier, being lost and re-conquered several times. Due to its location on a pass that separates the mountains Mosor and Kozjak, the fortress served as a major source of defense in Dalmatia, especially against the Ottoman advance, and has been a key crossroad between the Mediterranean belt and the Balkan rear.
Since Duke Mislav of the Duchy of Croatia made Klis Fortress the seat of his throne in the middle of the 9th century, the fortress served as the seat of many Croatia"s rulers. The reign of his successor, Duke Trpimir I, the founder of the Croatian royal House of Trpimirović, is significant for spreading Christianity in the Duchy of Croatia. He largely expanded the Klis Fortress, and in Rižinice, in the valley under the fortress, he built a church and the first Benedictine monastery in Croatia. During the reign of the first Croatian king, Tomislav, Klis and Biograd na Moru were his chief residences.
In March 1242 at Klis Fortress, Tatars who were a constituent segment of the Mongol army under the leadership of Kadan suffered a major defeat while in pursuit of the Hungarian army led by King Béla IV. After their defeat by Croatian forces, the Mongols retreated, and Béla IV rewarded many Croatian towns and nobles with 'substantial riches'. During the Late Middle Ages, the fortress was governed by Croatian nobility, amongst whom Paul I Šubić of Bribir was the most significant. During his reign, the House of Šubić controlled most of modern-day Croatia and Bosnia. Excluding the brief possession by the forces of Bosnian King, Tvrtko I, the fortress remained in Hungaro-Croatian hands for the next several hundred years, until the 16th century.
Klis Fortress is probably best known for its defense against the Ottoman invasion of Europe in the early 16th century. Croatian captain Petar Kružić led the defense of the fortress against a Turkish invasion and siege that lasted for more than two and a half decades. During this defense, as Kružić and his soldiers fought without allies against the Turks, the military faction of Uskoks was formed, which later became famous as an elite Croatian militant sect. Ultimately, the defenders were defeated and the fortress was occupied by the Ottomans in 1537. After more than a century under Ottoman rule, in 1669, Klis Fortress was besieged and seized by the Republic of Venice, thus moving the border between Christian and Muslim Europe further east and helping to contribute to the decline of the Ottoman Empire. The Venetians restored and enlarged the fortress, but it was taken by the Austrians after Napoleon extinguished the republic itself in 1797. Today, Klis Fortress contains a museum where visitors to this historic military structure can see an array of arms, armor, and traditional uniforms.